Abstract:As a food additive strictly certified by the state, octacosanol is rich in herbal resources, in addition to a variety of pharmacological activities such as lowering blood lipids, anti-fatigue, and prevention of cardiovascular diseases. At present, the use of nanometer, microencapsulation, cyclodextrin encapsulation and other high-tech has effectively improved the bioavailability of octacosanol, and promoted its wide application in the fields of medicine, health care, food and feed. However, due to the late start of the research on octacosanol in China, coupled with the technical limitations, its related extraction process, resource development and large-scale production are yet to be studied in depth. In this paper, the natural plant resources of octacosanol are summarized, and their preparation, synthesis, in vivo absorption and metabolism, and pharmacological effects are reviewed; at the same time, the bibliometric method is applied to analyze the research trends and hotspots of octacosanol at home and abroad, to provide theoretical bases for the exploitation and utilization of octacosanol resources and the research and development of octacosanol products.
