Research Progress on the Preparation and Biological Activity of Platycodon grandiflorum Polysaccharides
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Abstract:
Platycodon grandiflorum, a perennial plant of Campanulaceae, and its root has a long history of edible and medicinal use. It is one of the large medicine-food homology species with important research values. P. grandiflorum root is often salted as pickles in Northeast and North China, which are in great market demand. The dried root is often used in the clinical treatment for symptoms such as cough, phlegm, chest tightness, sore throat, hoarseness, and pulmonary carbuncle. The existing research shows that P. grandiflorum contains abundant functional polysaccharides, which play a vital role in immunomodulation, anti-inflammation and cough relieving, thereby having important research and development prospects. However, current studies in China and abroad focused mainly on the structure and biological activity of P. grandiflorum, and there is no systematic literature review on P. grandiflorum polysaccharides. In this paper, the latest research progress of P. grandiflorum polysaccharides was systematically categorized and summarized by reviewing the domestic and overseas research literature on the extraction, isolation, purification and biological activity of P. grandiflorum polysaccharides, which provides a reference for further research and in-depth development and utilization of P. grandiflorum polysaccharides.