Research Progress on the Regulatory Functions of Grifola frondosa Polysaccharides in Lipid Metabolism
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Abstract:
Grifola frondosa is one of edible and medicinal fungi, containing many active ingredients that are beneficial to human beings. The polysaccharide of Grifola frondosa is a kind of functional polysaccharides with unique structure and multiple bioactiviites. It can ameliorate abnormal lipid metabolism caused by high calorie diet, has the characteristics of low toxicity, wide-spectrum function and many targets in regulating lipid metabolism. Lipid metabolism disorder refers to the abnormality of lipids and their metabolites in the blood and other tissues. High-fat diet, lack of exercise, metabolic syndrome and other factors can cause the occurrence and development of lipid metabolism disorder, which seriously harms human health. Lipid metabolism disorder may lead to dyslipidemia, arteriosclerosis and obesity, which can seriously affect health and even threaten life. In recent years, many natural polysaccharides have been used as prebiotics to prevent metabolic disorders through regulating the expression of key genes and gut microbiota. Grifola frondosa polysaccharide can be used as a functional food to treat or prevent hyperlipidemia, arteriosclerosis and obesity. This paper explores the effects of Grifola frondosa polysaccharide on lipid metabolism from the aspects of regulating triglycerides, fatty acids and cholesterol metabolism as well as gut microflora structure.
