Osteogenic Mechanism of Action of Strontium and Research and Development Status of Strontium-rich Foods

Abstract:

Strontium is an essential trace element widely distributed in human tissues, with bone being its largest "reservoir", in which approximately 99% of strontium is present in the ionic form. Strontium has a considerable impact on bone health, and hence there is wide research consensus that the clinical drug strontium ranelate can protect bone health by influencing bone metabolism. However, as it is a synthetic chemical that is less safe than natural strontium salts, the development of strontium-rich foods which will aid individuals to care for their bone health through their daily dietary routine, has garnered increasing research attention. This paper reviews the types of common orthopedic diseases, the mechanism of action of strontium on bone metabolism, and the current status and development of food-based strontium products, focusing on the dual osteogenic mechanism of strontium regulating both osteoblasts and osteoclasts and the current situation of strontium-rich foods. The findings of this study providea theoretical basis for the application of strontium in orthopedic diseases and the improved development of strontium-rich foods.