Effects of a Red Ginseng and Donkey-Hide Gelatin Composite Beverage on Hematopoietic Ability and Immunomodulatory Function in Mice
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Abstract:
Red ginseng and donkey-hide gelatin peptide were used as the main functional raw materials to develop a functional composite beverage, into which auxiliary materials were added, including collagen peptide, yeast β-glucan, N-acetylneuraminic acid, chicken peptide, longan powder, red date powder, and γ-aminobutyric acid, according to the National Solid Beverage Standards. The antioxidant effects of the beverage were detected in vitro, and a mouse model of Qi and blood deficiency was constructed to determine the effect of the beverage on immune function. The results show that the total antioxidant capacity of the beverage at 100 mg/mL was 0.25 U/mL. In addition, the beverage restored the number of leukocytes, lymphocytes, and platelets in mice with Qi and blood deficiency. The beverage also significantly alleviated spleen damage, reduced MDA contents, and enhanced the activities of antioxidant enzymes (superoxide dismutase and glutathione peroxidase), thereby reducing oxidative damage. Furthermore, the beverage could significantly improve antioxidant capacity, hematopoietic ability, and immunomodulatory function in mice. Overall, the functional beverage had abundant beneficial effects and shows promise as a marketable multifunctional food in the future.