Research Progress on Iron Absorption in Human Body and Unique Properties of Plant Ferritin for Iron Supplementation
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Abstract:
Iron-deficiency anemia is still one of the public problems related to health nutrition currently facing the world, and the nutritional function of iron is closely related to its absorption and utilization in the body. Plant ferritin, with its unique cage structure, has broad application prospects in iron supplementation. This article reviews mainly the absorption pathways of iron from various sources by the human body, the structure of plant ferritin and its characteristics as an iron supplement. Regarding the ways of iron absorption in the body, a focus is placed on the absorption approach in the human body for iron from various sources, such as heme iron and non-heme irons like Fe2+, Fe3+ and ferritin. Moreover, the factors affecting the iron absorption were also reviewed. Then, the basic structure of plant ferritin and its special structure compared with animal ferritin are described. Finally, t he iron supplementation characteristics of plant ferritin exhibited in cell experiments, animal experiments and clinical research, and its application in the field of ano-encapsulation are summarized. The purpose of this review is to lay a foundation for in-depth study on the body’s iron metabolism and nutritional characteristics of plant ferritin.