Progress on the Detection Methods of Deoxynivalenol in Grain
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Abstract:
It is known that deoxynivalenol (DON) has immunotoxicity, organotoxicity, inhibition of protein synthesis and teratogenicity. Grain under improper storage conditions is easily contaminated by mold which produces DON. DON can cause serious health problems after ingested by humans or animals. DON is stable and difficult to be destroyed and removed in the processing process, which is an important and potential safety hazard in the grain production and processing. There is a serious problem that DON exceeds the maximum residue limit in grain in China. Therefore, accurate and efficient DON detection methods are of great importance to ensure grain safety and human health. In this paper, the main methods for the detection of DON in cereals in recent years were summarized, including thin layer chromatography, high performance liquid chromatography-mass spectrometry, enzyme-linked immunoassay, lateral flow immunoassay strips, Raman spectroscopy, electrochemical method, surface plasmon resonance method, etc. The advantages and disadvantages of these detection methods were discussed and compared. At last the development trend of DON detection methods was prospected. It could provide theoretical support for the development of new detection methods, and is conducive to promoting the application of accurate and rapid detection methods in food safety detection.
