The Relationship between the Structure and Function of Dendrobium Polysaccharides: a Review
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Abstract:
Based on the high content of polysaccharides in Dendrobium, the structure and activity of Dendrobium polysaccharides have been studied deeply in recent years. In this review, the monosaccharide composition, glycoside bond, acetyl group and branching degree of Dendrobium polysaccharides have been sorted out. The mechanism of activity of Dendrobium polysaccharides in antioxidant, immunomodulatory and anti-diabetic activities has been summarized. This paper calculated the EC50 value of free radicals scavenging DDPH Dendrobium polysaccharides with antioxidant activity, and established a random forest model from the point of view of the composition and relative abundance of polysaccharides monosaccharides of Dendrobium officinale with antioxidant activity. The model predicted the antioxidant activity of Dendrobium polysaccharides, and the accuracy of the model was 70.00%. The results showed that the monosaccharide which had the greatest influence on the antioxidant activity of Dendrobium polysaccharides was glucose. The linear relationship between the antioxidant activity of Dendrobium polysaccharides, mannose and galactose and the linear relationship between mannose and arabinose was related. This paper provides a reference for exploring the qualitative and quantitative relationship between polysaccharide activity of Dendrobium officinale with different structures.