Chemical Structure Characterization and Biological Activity of Mumefural from Prunus mume: a Review
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Abstract:
Prunusmume Sieb. Et Zucc is an important characteristic fruit in China, which is of high acidity and mainly used for processing into food or Traditional Chinese medicine. Mumefrual is the product in the processing process of Prunusmume. Recently, a lot of abroad studies have focused on the biological activity of Prunusmume products rich in mumefrual, such as juice concentrate. The chemical structure characterization, formation mechanism and biological activity of mumefrualand its derivatives were described in detail. The chemical structure of the mumefrual is 1-[5-(2-formylfuryl) methyl]-dihydrogen 2-hydroxypropane-1,2,3-tricarboxylate. Three kinds of its derivatives were found, which were esterified by the reaction of organic acids such as citric acid and malic acid with 5-hydroxymethyl furfural. In this paper, the main biological activity and its underlying molecular mechanisms such as improving blood flow, lowering blood pressure, inhibitory effects on influenza virus, and ameliorates cognitive impairment were discussed. In addition, this paper briefly introduced the mumefural purification technology, positive effects on fatigue and bowel movements, antioxidant activity, and contribution rate of biological activity of mumefural, how to improve the mumefural content in product, and mumefural identification problem. This review will provide inferences for Prunusmume deep processing.
