Comparison of Anti-aging Effects of Portulaca oleracea L. from Different Areas
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Abstract:
To study the differences in chemical compositions and activities of Portulaca oleracea L. (PO) from different areas, four PO from different areas were selected as samples. The Folin-Ciocalteu, SBC and ORAC method were used to determine the total phenol content, total flavonoid content and the antioxidant value, and the effect of the sample on the life extension of nematodes was studied by C. elegans model. The results shows that PO Sichuan has the highest effect based on four indicators: total phenol content 99.28 μg GAE/mg DW, total flavonoid content 121.57 μg CE/mg DW, ORAC value 3.32 μmol Trolox/mg DW, it can prolong the mean lifespan from 19.53 days to 26.65 days, with an increase of 36.49%. The longevity effect is in a dose-dependent manner. Through correlation analysis, ORAC has a strong correlation with total flavonoid content (R2=0.99), and the antioxidant activity of the PO alcohol extract can be used as an index affecting its effect on prolonging the life of nematodes (R2=0.95). In summary, PO has good anti-aging effects, while PO from Sichuan has the best effect, and has great development potential. The anti-aging effect that alcohol extracts from PO acts in the nematode model is probably promoted by the sample antioxidant activity, which has high correlation with the flavonoid content.
