Abstract:The effect of the nanoemulsion complex of Euphausia superba oil and Ganoderma lucidum spore oil on immune function in mice was investigated. Compared with the negative control group, the nanoemulsion complex in the low and medium dose groups improved the splenic lymphocyte transformation capacity by 35.72% (p<0.05) and 157.13% (p<0.01), respectively; in the high dose group, the effect of DNFB-induced delayed allergic reaction in mice was enhanced by 32.41% (p<0.05). The proliferation of mouse antibody-generating cells in the medium dose group was promoted by 21.12% (p<0.05), and the productions of serum hemolysin in mice at low, medium and high doses were enhanced by 63.22% (p<0.01), 77.64% (p<0.01), and 55.31% (p<0.01), respectively. The NK cell activities of mice in the medium and high dose groups were 58.29% (p<0.01) and 134.83% (p<0.01), respectively. Cellular immune function, humoral immune function and NK cell activity were all positive. The nanoemulsion complex of Euphausia superba oil and Ganoderma lucidum spore oil enhanced the immunity of mice.
