Relieving Physical Fatigue of Sea Cucumber Peptide Complex
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Abstract:
The was investigated effect of the compound of sea cucumber peptide, Maca powder, Wolfberry extract and Rhodiola rosea extract on relieving physical fatigue. Four hundred of healthy male mice were divided into 4 batches (N=100), on which weight loading swimming experiment, serum urea nitrogen test, blood lactic acid test, and liver glycogen test after exercise were conducted respectively. Each batch was randomly divided into 10 groups (n=10), one of which was used as the negative control group, and the other 9 groups as the low, medium and high dose of three experimental groups (sea cucumber peptide complexes, sea cucumber peptide, plant extracts). Low (0.2 g/kg?bw), medium (0.4 g/kg?bw), and high (1.2 g/kg?bw) doses are equivalent to 5, 10, and 30 times the recommended doses of the human body. The drug was administered by intragastric administration once a day for 30 days, and the control group was given an equal amount of distilled water. The changes of exhaustive swimming time, serum urea nitrogen content, lactate levels and hapatic glycogen content after exercise in each group were compared. Compared with the control group, the weight loading swimming times of the groups administered the medium and high-dose sea cucumber peptide complexes was extended by 80.06% (p<0.05) and 99.13% (p<0.01) respectively. In the meantime, the serum urea concentrations after exercise decreased by 26.21% (p<0.05) and 30.74% respectively (p<0.05), the area under the curve of blood lactic acid were reduced by 26.90% (p<0.05) and 32.11% (p<0.05) respectively. It can be seen that the sea cucumber peptide has better effect on relieving fatigue by compounding with Maca powder, Wolfberry extract and Rhodiola rosea extract.
