Controlled Bioactive Compound Delivery Systems for Liquid Food and Their Release Behaviors
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Abstract:
The storage stability and controlled release of bioactive compounds were achieved through microencapsulation controlled release delivery system. The film-coated microparticle delivery systems for liquid food based on resistant starch acetate (RSA) were established by the methods of extrusion-spheronisation and fluid-bed spray coating. The releasing properties during yoghurt storage and in vitro simulated gastrointestinal tract environment of RSA-coated microparticles with different thickness were investigated. Results showed that under the same storage time, the larger coating thickness was, the more intact coating layer would be, which could prevent the release of bioactive compounds. When the thickness of the film-coated is 9.94%, the bioactive compounds did not release during storage for 22 days. Additionally, after storage in yogurt, the change of the surface morphology of microparticle with different coating thickness in the simulated gastrointestinal tract environment was consistent with their release. The results provide a theoretical basis and basic data for screening suitable carrier materials for bioactive compounds and its target-controlled delivery system for liquid foods.
