Study on the Lipid-lowering Effect of Xiang Qi Lower Blood Lipids Chewable Tablet
Article
Figures
Metrics
Preview PDF
Reference
Related
Cited by
Materials
Abstract:
The effects of Xiang Qi lower blood lipids chewable tablet on body weight, blood lipids and liver function in hyperlipidemia model mice were investigated in this work. Sixty male Institute of Cancer Research mouse were randomly divided into 6 groups: normal group (normal saline), model group (normal saline), simvastatin-positive group (5 mg/kg), and Xiang Qi lower blood lipids chewable tablet high dose (2 g/kg), medium dose (1 g/kg) and low dose (0.5 g/kg) groups. The normal group was fed with normal feed, and the other groups were fed high-sugar and high-fat feed. Oral administration during the experiment, and various experimental indicators were measured after 6 weeks. The hyperlipidemia model obtained with this modeling method has little effect on the body weight of mouse. Compared with model group, total cholesterol, low-density lipoprotein, aspartate aminotransferase and alanine aminotransferase of the hyperlipidemia mouse serum of decreased Xiang Qi lower blood lipids chewable tablet groups with the largest reduce rates of 28.85%, 37.90%, 25.08% and 42.09%, while high-density lipoprotein increased with the highest growing rate of 73.70%. The results demonstrated that Xiang Qi lower blood lipids chewable tablet has the function of hypolipidemicing and protecting liver, and this effect is most obvious in high dose (2 g/kg).
