Comparison on the Antioxidant Activity and Tyrosinase Inhibitory Effect of Five Natural Plant Extracts
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Abstract:
This study examined the in vitro antioxidant activity and tyrosinase inhibitory effect of five natural plant extracts, analyzed the flavonoid and total phenolic contents, and explored the correlation between whitening effect and antioxidant activity of extracts. The results of ABTS+, DPPH+, hydroxyl and superoxide anion radical scavenging assays revealed that the five extracts all possessed some antioxidant activity but their potencies different. At the same time, tyrosinase inhibition assay showed that these extracts all had some inhibitory effects on enzyme activity. The antioxidant activities and tyrosinase y inhibitory capacities of the five plant extracts increased with elevated concentrations of the sample. These results suggest that the antioxidant capacity of the extract is related to its inhibitory effect on tyrosinase activity, which may be associated with flavonoids and total phenolics in the extracts. When ABTS+ and DPPH+ methods were used, the antioxidant activities of the five extracts were related closer to their corresponding tyrosinase inhibitory effects. This finding may be associated with the inhibitory functions of flavonoids and phenolics towards tyrosinase activity. The research results provide a theoretical basis and reference for the screening and development of natural whitening plant-based raw materials.
