Effect of the Compound Tartary Buckwheat Flour on the Defecation in Mice
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Abstract:
Compound buckwheat powder can effectively improve intestinal peristalsis and promote defecation, improve constipation. Effects of the compound tartary buckwheat flour on the defecation were investigated by the laxative efficacy test in mice. Kunming mice were randomly divided into 5 groups, including blank control group, constipation model group, and compound tartary buckwheat flour in the low, middle and high dose groups. The mouse constipation model was established by intragastric administration of diphenoxylate. The effect of compound tartary buckwheat flour on the defecation function was evaluated by measuring the intestinal propulsion rate, first black feces time, the number of black feces in 6 hours and feces weight. After the mice were subjected to continuous intragastric infusion for 14 days, ink-pushing rate in high dose group was significantly higher than that in the constipation model group (p<0.05); the number of black feces in high dose groups was higher than that in the constipation model group (p<0.01), and the number of black feces in low and middle dose group revealed a significant increase when compared with that in the constipation model group (p<0.05); compared with the model group, the feces weight in each compound tartary buckwheat flour treatment groups were higher (p<0.01); however, there were no significant differences on the first defecation time between the compound tartary buckwheat flour treatment groups and the constipation model group. Compound tartary buckwheat flour could effectively improve defecation and intestinal peristalsis.
