Research Progress and Application of Plant Antimicrobial Peptides
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Abstract:
Antimicrobial peptides (AMPs) are an important part of innate immune system of organisms, which are isolated from a wide range of organisms, including bacteria, plants and animals. In the past 20 years, the number of antimicrobial peptides has been increasing rapidly and their broad spectrum antimicrobial activity is also being studied in depth with the continuous discovery of antimicrobial peptides, Plant AMPs are isolated from plants, showing many differences with other life forms of AMPs. Common types of plant AMPs include thionins, plant defensins, Heveins, Knottins, lipid transfer proteinsand and Snakins. Because of the increasing antibiotic resistance of pathogenic microorganisms, there is an urgent need to find alternatives of traditional antibiotic agents. Plant AMPs have the potential to be the drug candidates of animal and human’s infection caused by pathogens for their wide range of biological activities including antibacterial, antifungal, antiviral, anticancer and insecticidal.. The mechanism of antibacterial activity of plant AMPs is an important direction of our research, which is helpful to find a new therapy for disease. In this study, we provide an overview of all plant AMPs with their classification types, distribution, function, mechanism of microbial resistance to plant AMPs and development prospects.
