Radish Seed Oil Characteristics and Laxative Effects in Mice
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Abstract:
The composition of radish seed oil and its laxative effects in mice were investigated. The physicochemical indices, fatty acid composition, and the content of various active substances were measured using chemical methods. High, medium, and low dosages of radish seed oil were administered to mice by gavage, and the fecal mass, number of fecal pellets, time of the first black pellet, and ink propulsion rate were determined. Several types of fatty acids were identified in radish seed oil, including 36.18% erucic acid, 20.22% linolenic acid, 19.80% oleic acid, 12.35% linoleic acid, and small amounts of other fatty acids. Unsaturated fatty acids accounted for 88.74% of the total fatty acids. The content of tocopherol, sulforaphene, and sterol in radish seed oil was 1.5984 mg/g, 55.35 mg/kg, and 14.3201 mg/g, respectively. Replacing the soybean oil in basal feed formula with 25~100% radish seed oil showed a significant anti-constipation effect in mice. Mice gavage-fed with radish seed oil at 1.0~3.0 g/(kg?bw) showed significantly improved small intestine peristalsis when constipated. Constipated mice were almost cured by radish seed oil doses of 2.0~3.0 g/(kg?bw). Radish seed oil has several beneficial qualities, including anti-constipation effects, and shows a broad application prospect.
