Effects of Banana Powder on Blood Glucose and Insulin Resistance in a Rat Model of Type II Diabetes Mellitus
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Abstract:
The effect of banana powder on blood glucose and insulin resistance in streptozotocin-induced type II diabetic rats was studied. Sprague-Dawley (SD) rats were divided into normal control group (NCG), diabetic control group (DCG), diabetic group with banana powder intervention (DBG), and normal group with banana powder intervention (NBG). After eight weeks of intervention, the fasting blood glucose of DBG rats was reduced by 32.75%, their glucose tolerance improved, and their weight was increased by 7.92% (all when compared with DCG rats). DBG rats also showed dramatic decreases in total cholesterol, triglyceride ester, free fatty acids, and low-density lipoprotein by 50.65%, 79.63%, 60.38% and 39.71%, respectively; as well as an 86.96% increase in the ratio of high-density lipoprotein:total cholesterol, and a normalization of blood lipid content (all in comparison to those of DCG rats). Further, compared with DCG rats, the plasma insulin and insulin resistance index of DBG rats were significantly reduced by 25.18% and 51.28%, respectively, and the insulin sensitivity index and pancreatic β-cell function of DBG rats were increased by 14.87% and 38.31%, respectively. This study indicates that banana powder shows a certain capability to regulate blood glucose, mitigate weight loss, and effectively improve lipid metabolism disorder and insulin resistance in diabetic rats.
