Progress in Functional Lipid Nanodispersion Research
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Abstract:
Functional lipids such as carotenoids, phytosterols, lipid-soluble vitamins, and n-3 polyunsaturated fatty acids, have high nutritional value and important physiological functions. However, the use of functional lipids in the food and pharmaceutical industries is restricted due to its low solubility resulting in poor absorption in the gastrointestinal tract and low bioavailability in the digestive system from food containing functional lipids. Therefore, improving water solubility, stability during storage, and bioavailability of functional lipids is an immediate requirement. Functional lipid nanodispersions, prepared by using nanotechnology have the potential to improve the solubility and bioavailability of functional lipids, thus expanding the use of functional lipids in the food industry. Based on previous reports on functional lipid nanodispersions in literature, the authors present a review of the requirements and preparation methods for functional lipid nanodispersions. Additionally, the factors affecting the physicochemical stability of functional lipids in the nanodispersion system as well as the bioavailability and food safety of functional lipid nanodispersions are discussed. Finally, the scientific issues and areas of current research on functional lipid nanodispersions are summarized and the prospect of future research is discussed.