Antifatigue and Antioxidant Effects of Spiraea salicifolia L. Leaf Decoction in Mice
Article
Figures
Metrics
Preview PDF
Reference
Related
Cited by
Materials
Abstract:
Antifatigue and antioxidant effects of Spiraea salicifolia L. leaf decoction in mice were investigated in this paper. Mice were randomly divided into different groups, and each group was administrated with different doses of .S. salicifolia L. leaf decoction by gavage; a blank control group was set up. The antifatigue effect of S. salicifolia L. leaf decoction was studied by the measurement of the weight-loaded swimming time, hepatic glycogen content, muscle glycogen content, serum urea nitrogen level, and lactate level in whole blood of mice; the levels of catalase and superoxide dismutase were measured in mice to study the antioxidant effect of the decoction. Compared with the blank control group, the changes of each indicator in mice administered low, medium, and high doses of S. salicifolia L. leaf decoction were as follows: the weight-loaded swimming time increased by 52.19%, 167.11%, and 197.37%, respectively; the hepatic glycogen content increased by 68.94%, 167.09%, and 195.81%, respectively; the muscle glycogen content increased by 3.28%, 19.67%, and 27.87%, respectively; the serum urea nitrogen level decreased by 14.89%, 19.54%, and 35.27%, respectively; the lactate level in whole blood decreased by 14.59%, 22.84%, and 33.21%, respectively; the catalase level increased by 15.48%, 25.40%, and 53.57%, respectively; the superoxide dismutase level increased by 19.59%, 26.31%, and 38.29%, respectively. Studies demonstrated that S. salicifolia L. had antifatigue and antioxidant effects; it could be used as a raw material for functional and healthy products and had certain development and utilization values.
