Detection and Characterization of Gizzerosine in Fish Meal
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Abstract:
Gizzerosine (GZ) in fish meal feed is the causative agent of gizzard erosion and ulceration, inappetence, decreased spawning rate, Black Vomit, and death in chickens, ducks, fish, and other poultry. Gizzerosine is a biogenic amine formed during the flame-drying treatment of brown fish meal. The level of gizzerosine that can cause pathological changes is about 1 mg/kg and its physiological toxicity is 1000 times that of histamine in fish meal. The main pathogenic mechanism is that gizzerosine promotes secretion of large amounts of gastric acid, resulting in gastric mucosal lesions. Poultry farming is the main source of income in agriculture field, and is an important contributor to food-related human health. From the safety point of view in animal husbandry, it is essential to establish an inspection system that is suitable to monitor feed safety affording timely and effective control of factors affecting poultry safety. In this study, the physicochemical properties, toxicity levels, and gizzerosine detection methods were reviewed in the paper, thereby providing a reference for future research on gizzerosine and methods to control the diseases it causes. Thus, it offers a new perspective for gizzerosine-related research.
