Effects of Different Processing Conditions on the Existing Pattern of Sialic Acid in Infant Formula
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Abstract:
Sialic acid is rich in human milk, and it plays an important role in infants’ growth and development. However, the study on the adding of sialic acid to infant formula was less reported. In order to make sialic acid content in infant formula closer to breast milk, sialic acid adding to infant formula by dry and wet process and the adding dosage of sialic acid in infant formula were determined. The results showed that one ton of infant formula made by dry process should be added from 1400 to 2800 g free sialic acid, and the content of sialic acid in infant formulas were 348~559 mg/L. Adding dose of free sialic acid in infant formula milk powder by wet method was 400~800 mg/L, and the content of sialic acid in infant formulas were 343~557 mg/L. Although the two technologies could meet the content of sialic acid in infant formula standards, but dry process was more economic. The present study also suggested that the proportion of glycoprotein-bound-sialic acid was decreased with the increasing of adding doses of free sialic acid. When adding dose by dry process was 2.8 kg/t and 800 mg/L by wet peocess, the sialic acids in infant formula was close to the existing pattern of sialic acids in human milk.
