Abstract:Biodegradable polymer of polyvinyl alcohol (PVA) and cinnamon essential oil with a good antimicrobial effect were successfully electrospinned into antimicrobial nanofiber film in this study. The solution composition and electrospinning parameters had significant effect on the distribution of fiber diameter，leading to the variation of antimicrobial property of nano-material. Therefore, we first investigated the effect of PVA and β-cyclodextrin (β-CD) concentrations on the fiber diameter distribution. SEM was applied to observe the morphology of the nanofibers, and the optimal mass concentration of PVA and β-CD was found to be 6% and 2%, respectively. SPSS methodology was used to analyze the effect of the flow rate and distance on the diameter distribution under constant voltage condition The results showed that the distance had more remarkable influence on the nanofiber diameter than that of flow rate. The optimal electrospinning conditions were: voltage 15 kV, flow rate 0.4 mL/h and distance 14 cm. Under the above-mentioned optimal conditions, the diameters of the resulting nanofibers were equally distributed, and the nanofiber film had a good morphology, which could enhance the persistence of its antimicrobial ability.
