An Empirical Model for Predicting Conversion of the Synthesis of n-Butyl Lactate by Lipase-Catalyzed Esterification
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Abstract:
Butyl lactate is an important green solvent, which was widely used in food and cosmetic industries. Enzymatic process for the synthesis of butyl lactate provides high-efficient manufacture. An empirical model for predicting conversion of the synthesis of n-butyl lactate by lipase-catalyzed esterification was proposed based on the relationships of reaction time, reaction temperature and lipase concentration in a given n-butyl alcohol/lactic acid molar ratio (1.5:1). The model of Er, % = 0.168×D0.018×(T-7.5) ×Ln(1+100t) was established, with a good correlation (R2 = 0.995) between the experimental data and predicting data. Such data would be valuable for the process control and optimization during the synthesis of n-butyl lactate.
