Antagonism Effects of a Compound Functional Beverage with Camellia sinensis L. and Morus alba L. on D-Galactose Induced Oxidative Damage in Mice
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Abstract:
The present study mainly investigated the dry powder of compound functional beverage with Camellia sinensis L. and Morus alba (DPCB) on D-galactose induced oxidative stress in mice, and determined the changes of body weight, viscera index, serum and liver MDA content, GSH-Px, SOD activities, and hepatic histopathology. The results indicated that the body weight gain, thymus index, spleen index, liver index, and kidney index in different dose groups of DPCB significantly increased ,compared with the oxidative stress model group. The serum and hepatic MDA content in high dose DPCB mice decreased 21% and 15%, respectively, compared to oxidative stress mice. DPCB could increase the serum and hepatic GSH-Px and SOD activities in a dose-dependent manner. In addition, DPCB could protect the hepatic histopathologic changes. This study laid a foundation for DPCB exploitation to antioxidant functional foods.
