Abstract:The plant of Laggera pterodonta was powered, extracted with ethanol and purified by silica gel column chromatography. The purity of the compounds from the plant was investigated by HPLC and their structures were identified on the basis of spectral analysis. Then the antioxidant activity of the compounds was evaluated by DPPH radical scavenging assay. Artemitin and chrysosptertin B were separated from Laggera pterodonta, which showed antioxidant activity lower than vitamin C.