Optimizition of Microwave Assisted Extraction of Total Flavone from Sonchus oleraceus L.
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Abstract:
A new method for extracting total flavone from Sonchus oleraceus L. was developed by microwave assisted extraction and the flavone content was measured with NaNO2-Al(NO3)3 colorimetry. The effects of influencial factors on total flavone ethanol concentration were discussed and the parameters were optimized by means of single factor test and orthogonal designed experiments. Results showed that the impact order of the influence factors was extraction time>solid/liquid ratio>ethanol concentration. The obtained optimum conditions for total flavone extraction were ethanol concentration 40%, dealing time 8min and the ration of material to solvent 1:30. The flavone yield under the optimum conditions was 19.6 mg/g.