Blood Pressure Lowering of Se-riched Soybean Oligopeptides
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Abstract:
To study the effect of Se-riched soybean oligopeptides in lowering blood pressure, 90 male SD rats of 5 weeks old were randomly divided into 4 groups and had been fed according to the design. The body weight and blood pressure of those rats were determined at the weekend. After feeding for 4 weeks, all of the rats were sacrificed at the next day of stopping feeding and the ACE activity in serum and lung tissue, as well as the content of K, Na and Se in serum were measured. Results showed that Se-riched soy oligopeptides can promote the body weight of the experimental rats, reduce the ACE activity in serum, but showed little effect on the ACE activity in lung tissue. Se-riched soy oligopeptides can l decrease concentration of Na ion in serum and increase the content of Se in serum, indicating that they can decrease blood pressure of SHR which were due to the combined effects of Se and soy oligopeptides. Except that the ACE activity has been inhibited, the decreased of Na+ and the increase of the content of Se may also lead to the decrease of the blood pressure of SHR.
