Abstract:The slurry was treated by ultrasonic cell disrupter, and the experiment was verified. Response surface design was generated by the Design-Expert software according to the central composite design principle and a mathematical model was set up. The optimal extraction conditions were found as liquid-to-solid ratio of 28:1 and ultrasonic time of 6s and 40 times and time interval of 2s. Under these conditions, the yield of SOD was 359.54 U/g, and compared with the model prediction, the error was 1.01%.
