The Biological Activities of Chitosan Oligosaccharide Derivatives prepared by Maillard Reaction
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Abstract:
Two kinds of chitosan oligosaccharide derivatives (CG and CM) were prepared by Maillard reaction of chitosan oligosaccharide (COS) with glucose and maltose, respectively. The molar ratio of amino group of COS and carbonyl group of glucose (maltose) was 1:1. The structural changes of CG and CM were confirmed by fourier transform infrared (FT-IR) spectra, and their molecular weights were determined by gel permeation chromatography (GPC) method. The antioxidant and antibacterial activities of COS, CG and CM were also assessed. The FT-IR spectra of CG and CM showed the characteristic absorption peaks of COS. The antioxidant activity and the antibacterial activity of CG and CM against Escherichia coli, Pseudomonas aeruginosa and Vibrio parahaemolyticus were higher than those of COS, and CG prepared by COS and monosaccharide-glucose showed better antioxidant and antibacterial activity.
