Effects of DDVP on the Activity of GTP and GOP in Grass Crap
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Abstract:
Grass carps was exposed to an aquatic environment with DDVP concentration of 5~10 mg/L for 10 days. GTP and GOP activities in the kidney and liver of the fish were determined. The results showed that the LC50 of DDVP (96 h) to grass carp was 22.9 mg/L. The activities of GTP and GOP were determined in grass carp after exposure .The two enzymes in all tested tissues were induced in the initial exposure days, and then the enzyme activities decreased with increase of DDVP concentration and extension of exposure time, suggesting that the enzyme activities correlated to the DDVP concentration and the exposure time. GTP and GOP were sensitive to DDVP exposure in liver, which could be used as a more suitable biomarker for DDVP pollution.