Using grape seed as raw material,an instant powder was produced to fund a new way of utilization of the byproducts from grape wine enterprises. According to single factors test of thickener, baking temperature, the number of perfume effect on instant grape seed powders,the results of orthogonal experiment showed that the best thickener was β-dextrin and its dosage was of 80 mg?g-1.The best baking temperature, baking time, glucose dosage, citric acid dosage and sucrose fatty acid ester were 120 ℃, 40 min, 2.2%, 0.8%, and 0.14%, respectively. Under these conditions, the best product was abundant in aroma with pleasing flavor of the raw material.