Optimization of the Nuclease P1 Production Conditions by Penicillium citrinum in Solid State Fermentation
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Abstract:
The conditions for solid fermentation of a strain of Pecillium citrinum GX-K with high yield of nuclease P1 were studied. Wheat bran was US as the substrate of solid fermentation and the other optimum fermentation conditions were: 4% of sucrose, substrate-water ratio 1:0.9, fermentation temperature 30 oC and fermentation time 72 h. The activity of nuclease P1 under the optimum fermentation conditions reached 5783.41 U/g.
