Study of the Anti-obesity Function of Green Tea Extracts for Development of a Hypolipidemic Agents
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Abstract:
In this experiment, Fujian tea was treated by water extraction, alcohol extraction and alkaline extraction, giving crud polysaccharide, supernatant extracts, ethanol extracts and crude proteins. Using mice for the test animals by feeding them high-fat diet, high-fat obesity model was established. By setting model control and normal control groups, the weight-lose and lipid-lowering functions of four kinds of extracts were investigated. The results showed that, alcohol extract and the supernatant showed good effects on regulating blood lipids and weight control. Compared with model group, TG and body weight of the alcohol extract group decreased by 37.50% and 11.84%, respectively. TG and body weight of the supernatant extract group decreased by 35.42% and 7.32%, respectively. Compared with model group, crude protein and polysaccharide from Fujian tea showed lower lipid-lowering effec,. TC values of the mice in crude protein and polysaccharide groups decreased by 17.69% and 9.52%, respectively, and the LDL-C values of the mice decreased by 56.25% and 42.97%, respectively.In addition, HL activity in serum of the mice in ethanol extract group was significantly higher than that in the model group and the PL activity in serum of the mice in the supernatant group was significantly lower than that in the model group (P <0.01).
