The inhibitory activities of water extract, ethanol extract, and n-hexane extracts of loquat leaf on three common food contaminated bacteria (Escherichia coli, Staphylococcus aureus, Bacillus subtilis) were studied uses filter paper. And the minimum inhibitory concentrations of the three extracts were determined using the Gradient dilution method. The results indicated that these extracts had inhibitory effects on three test organisms, and the sequence of their bacteriostatic effects was ethanol extract >water extract >n-hexane extract. The Diameter of inhibited halo of 0.1 g/mL Ethanol extract on E. coli, Staphylococcus aureus and Bacillus subtilis were11.8 mm, 13 mm, and 11 mm, respectively. The minimum inhibitory concentrations of ethanol extract on the three bacteria were 0.1 mg/mL, 0.01 mg/mL, and 10 mg/mL, respectively.