Abstract:A method was developed for the determination of biphenol A, alkylpheniols and alkylphenol ethoxylates residues in nursing bottle by HPLC-RF. Samples were extracted by dichloromethane- methanol, and analyzed by HPLC-RF. The linear range of BPA, OP, NP, OPEO were within 0.05~1.0 µg/mL and that of NPEO was within 0.2~1.0 µg/mL. Recovery rates of these compounds in nursing bottle ranged from 81.1% to 100.3%, and the relative standard deviations were of 2.7%~5.5%. The detection limits of the method was: BPA 1 mg/kg, OP 2 mg/kg, NP 2 mg/kg, OPEO 2 mg/kg, and NPEO 5 mg/kg. This method was simple, sensitive and precise, which was suitable for qualitative and quantitative analysis of BPA、AP and APEO residues in nursing bottle.
