Abstract:The polysaccharides in leaves of Morus alba L., a kind of the main functional components of the Morus alba L. leaves, possesses various pharmacological and physiological activities and studies on this polysaccharides has become to a research hotspot in recent years. The research progress of extraction, isolation and purification, chemical constitution and bioactivities of the polysaccharides in mulberry leaves were reviewed in this paper, which is helpful to the further research and development of Morus alba L.