Antihypertensive Effects of Alcoholic Extracts from Salsola
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Abstract:
Objective: to study antihypertensive effects of alcoholic extracts from salsola using hypertension model rats induced by Nω-Nitro-L-Ariginine (L-NNA). Methods: For achieving murine hypertension models, L-NNA was intraperitoneal injected into rats, then different dose of the alcohol extracts were perfused into the stomach of rats. Result: In 2 weeks after giving the medicine, the pressure of the rats were decreased in different degree in three treated groups. There was statistically significant difference in comparison of the antihypertensive effects before and after giving medicine (all p<0.01). Conclusion: Alcoholic extracts from salsola had effective antihypertensive activity for rate induced by L-NNA. Its LD50, and its confidence limit of 95% were 14.5008 g/kg and 11.5455~18.2206 g/kg, respectively.
