Abstract:The random amplified polymorphic DNA（RAPD）is a rapid and sensitive method for analysis of characters of microbe. There is a promising prospect for the application of this technology to molecular identification and characterization, separation, purification, research on genetic relation among species or genus, volution of yeast, functional gene location, and the assistant breeding of Saccharomyces cerevisiae. In this paper, the application of RAPD to molecular classification and genetic breeding of Saccharomyces cerevisiae was examined and its disadvantages and the corresponding improvement methods were also discussed
