蜂蜜复合浓缩原浆的研制及其止咳化痰效果

Development of Honey-concentrated Pulp Composite and Its Cough and Phlegm Relieving Effect

摘要:

为提高蜂蜜等药食同源资源的开发利用，以蜂蜜、桑叶、玉竹、陈皮、桑椹、百合等为原料，研制一款具有止咳、化痰功效的蜂蜜复合浓缩原浆。以感官评价为指标，采用正交试验和响应面试验对产品配方及工艺进行优化。通过小鼠氨水引咳实验、酚红排泌实验对产品止咳、化痰功能进行评价。结果表明，蜂蜜复合浓缩原浆最佳配方为：蜂蜜添加量7.0 g、浓缩原浆添加量7.0 g、浓缩调味果汁添加量3.5 g。最佳加工工艺为：抽滤次数3次，浓缩时间60 min，浓缩温度60 ℃。产品能显著延长小鼠咳嗽潜伏期，减少2 min内小鼠咳嗽次数，提高小鼠酚红排泌能力，高、中、低剂量组咳嗽抑制率分别为36.18%、26.63%、26.38%。该研究制得的蜂蜜复合浓缩原浆风味独特，清甜宜口，具有良好的止咳化痰活性。

Abstract:

To enhance the development and utilization of honey, other medicine, and food homologous resources, this research developed a honey-concentrated pulp composite with antitussive and expectorant effects using honey, mulberry leaves, Polygonatum odoratum, dried tangerine peel, mulberry fruits, and lily bulbs. The formula and preparation process were optimized based on sensory evaluation results with the help of orthogonal design and response surface methodology. The antitussive and expectorant activities of the product were evaluated using ammonia-induced cough and phenol red excretion tests in mice. The results showed that the optimal formulation of the honey-concentrated pulp composite was as follows: 7.0 g of honey, 7.0 g of concentrated pulp, and 3.5 g of concentrated flavored juice, and the optimal process was as follows: three filtration cycles, concentration time of 60 min, and concentration temperature of 60 ℃. The product significantly prolonged the cough latency of mice, reduced the number of coughs in mice within 2 min, and improved the phenol red excretion ability of mice. The cough inhibition rates of high, medium, and low dose groups were 36.18%, 26.63%, and 26.38%, respectively. The honey-concentrated pulp composite developed had a unique flavor, a pleasant sweet taste, and good antitussive and expectorant activities.