Abstract:The demand for protein continues to increase due to the rapid growth of global population and improvement of living standards. Sesame is a widely planted oil crop in China, and is listed as an important crop in China’s modern agricultural industrial technology system. Sesame and the sesame cake after oil extraction are rich in protein, approximately 20% and 38%~50%, respectively. It was reported that sesame protein contains abundant essential amino acids and has a relatively balanced amino acid composition. Therefore, efficient utilization of sesame protein not only improves the resource utilization rate of sesame, but also is one of the important ways to ensure the balance of protein supply in China. This article focuses on summarizing the composition, nutritional value, extraction methods, structure and physicochemical properties, functional properties, modification approaches, and food processing applications of sesame protein, to provide support for the promotion of deep processing and high-value utilization of sesame protein.