[关键词]
[摘要]
玫瑰花是传统的理气药,具有行气、解郁、和血、止痛的功效。作为一类药食同源类中药,玫瑰花在我国有两千多年的栽培种植历史,分布范围广。其含有多种化学成分,主要包括挥发油、黄酮(如黄酮)、多酚、多糖、蛋白质、氨基酸等,现代药理研究表明,玫瑰花在抗氧化、抑菌、降血糖、降血脂、抗癌、抗肿瘤、预防心血管疾病和抗抑郁等方面表现出较强的生理活性。该文对玫瑰花的资源分布情况、化学成分和药理作用进行综述,并从植物亲缘学和化学成分特有性、化学成分可测性、传统药效和药性、化学成分和药理作用相关性等多方面对玫瑰花潜在质量标志物进行预测,表明香叶醇、香茅醇、苯乙醇、反-2-庚烯醛、2-甲基戊酸、二乙醇缩乙醛、2,6,10,15-四甲基十七烷、芹菜素、山奈酚、槲皮素可作为玫瑰花潜在质量标志物,以期为玫瑰花的质量控制提供参考依据。
[Key word]
[Abstract]
Rose, a traditional qi-regulating Chinese medicine, has the effects of moving qi, alleviating depression, harmonizing blood and relieving pain. As a class of food and medicine homologous Chinese medicines, roses have a history of cultivation and planting in China for more than 2 000 years and are widely distributed. Roses contain a variety of chemical components, mainly including volatile oils, polyphenols (e.g. flavonoids), polysaccharides, proteins and amino acids, etc. Modern pharmacological research showed that roses exhibit strong physiological activities in antioxidant, anti-bacterial, hypoglycemic, hypolipidemic, anticancer, antitumor, cardiovascular disease prevention and antidepressant aspects. In this paper, the resource distribution, chemical composition and pharmacological effects of roses are reviewed. The potential quality markers of roses are predicted from the aspects of plant genealogy, specificity of chemical composition and its predictability, traditional medicinal efficacy and medicinal properties, and the correlation between chemical composition and pharmacological effects. The results indicate that geraniol, citronellol, phenyl ethanol, trans-2-heptanol, 2-methylpentanoic acid, 1,1-diethoxyethane, 2,6,10,15-tetramethyldecapeptadecane, apigenin, kaempferol, and quercetin can be used as potential quality markers for roses, in order to provide a reference for the quality control of roses.
[中图分类号]
[基金项目]
甘肃省重点研发计划项目(23YFGA0012);兰州市人才创新创业项目(2020-RC-110);甘肃省高等学校产业支撑计划项目(2021CYZC-40);兰州市人才创新创业项目(2023-RC-9)