氢气是一种无色、无味、难溶于水且高度易燃的双原子气体，在某些情况下可充当还原剂。大量研究表明，氢气对代谢性疾病、神经退行性疾病、缺血再灌注损伤以及肿瘤等百余种疾病均具有潜在治疗作用。但是氢气在水中不仅溶解度低而且停留时间短暂，这也是限制富氢水广泛应用的主要因素，而纳米气泡由于内部压力高、表面带负电等特点可以增加氢气在水中的溶解度及停留时间，并增强其抗氧化能力。纳米气泡技术的发展也推动了国内外学者对氢纳米气泡水的研究以及开发应用，该文主要对现有氢纳米气泡水的最新研究进展进行总结概述，以期为氢纳米气泡水今后的应用研究提供参考。

Hydrogen is a colorless, odorless, water-insoluble and highly flammable diatomic gas that can act as a reducing agent in certain circumstances. A large number of studies have shown that hydrogen has potential therapeutic effects on more than 100 kinds of diseases, such as metabolic diseases, neurodegenerative diseases, ischemia reperfusion injury and tumors. However, hydrogen not only has low solubility in water but also has a short residence time, which is the main factor limiting the widespread application of hydrogen-rich water. However, due to their high internal pressure and negative surface charge, nanobubbles can increase the solubility and residence time of hydrogen in water, and enhance their antioxidant capacity. The development of nanobubble technology has also promoted the research, development and application of hydrogen nanobubble water by domestic and international scholars. This article mainly summarizes the latest research progress of hydrogen nanobubble water, in order to provide a reference for future application research of hydrogen nanobubble water.

国家重点研发计划项目（2021YFD1800600）；国家自然科学基金项目（32172914）；中央高校自主创新基金（2662022DKYJC005）