Abstract:Soft capsule, a popular dosage form for health food and drug, has several advantages, such as high bioavailability, easy to eat, bad smell-masking capability, wide application range and beautiful appearance. The recent advances in researches on the non-gelatin soft capsule shell compositions were reviewed, including the characteristics and applications of the main materials of starch, hydrocolloid and polymers, and excipient such as plasticizer. This paper provided a reference for the development and application of the new soft capsule.