绿茶饮料浓缩物缓解体力疲劳实验研究

Anti-fatigue Effects of Green Tea Beverage Concentrate in Mice

摘要:

目的：探讨绿茶饮料浓缩物缓解小鼠体力疲劳的作用。方法：240只清洁级雄性昆明小白鼠随机分为4组，分别以经口灌胃方式给予蒸馏水（对照组）、不同剂量绿茶饮料浓缩物[133 mg/(kgbw)，665 mg/(kgbw)，1995 mg/(kgbw)]，每日1次，连续45 d，进行负重游泳实验，测定血乳酸、血清尿素及肝糖原含量。结果：与对照组比，低、中剂量能够增加小鼠负重游泳时间（p<0.01）；低剂量组可降低游泳后即刻的血乳酸水平（p<0.05），各剂量组均能降低游泳后20 min的血乳酸水平（p<0.05）；中剂量组能够增加小鼠肝糖原储备（p<0.05）；各剂量组血清尿素水平没有明显变化（p>0.05）。结论：绿茶饮料浓缩物具有缓解小鼠体力疲劳的作用，以中剂量作用最强。

Abstract:

The anti-fatigue effects of green tea beverage concentrate in mice was studied by randomizing 240 Kunming mice to 4 groups, and oral gavage of distilled water (control group) or various doses of green tea beverage concentrate[133 mg/(kgbw), 665 mg/(kgbw), 1995 mg/(kgbw)] respectively, for consecutive 45 days. The loading swimming time, levels of lactate acid, serum urea, and liver glycogen were determined before and after swimming tests. Results showed that, compared with control group, administration of green tea beverage concentrate can significantly lengthen the swimming time (for low and medium dose groups, p<0.01), reduce the lactate acid level (immediately after swimming for the low dose group (p<0.05), 20 minutes after swimming for all dose groups (p<0.05), and increased the content of liver glycogen (for medium dose group, p<0.05), while no significant difference was found in serum urea level (p>0.05). It was concluded that green tea beverage concentrate may have anti-fatigue effects in mice, with strongest effects seen in medium dose group.