本文主要综述了微生物碱性蛋白酶在国内外的应用研究和现状，对微生物碱性蛋白酶的产生菌，碱性蛋白酶的应用、基因结构及性质，高产工程茵的选育技术等方面的研究进展进行了概述，并根据当前应用研究状况对微生物碱性蛋白酶在今后的发展进行了展望。

The current research status of microbial alkaline protease and its application at home and abroad were summarized. The producing strains, gene structure and properties of the alkaline protease, the screening and culturing of engineering strains with high production of the alkaline protease were introduced and the develop of alkaline protease was forecasted according to current applications studies.