Effect of Rose roxburghii Tratt Oral Liquid on Gastrointestinal Motility in Dyspepsia Mice
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Abstract:
To study the effect of R.roxburghii Tratt on gastrointestinal motility in indigestion mice. The successful mice were divided into model group (MC), positive group (PC), R.roxburghii Tratt oral solution (DF), R.roxburghii Tratt oral solution (HF) and normal group (NC). Normal group and model group were given normal saline, and positive group was given dofarione suspension. R.roxburghii Tratt oral liquid DF, HF groups were gavaged with oral liquid; the diet and body mass of mice were measured before and after the modeling. After the end of administration, the gastric residual rate, small intestinal motility rate, serum motilin MTL and gastrin GAS were measured to evaluate the effect of promoting digestion. It was found that compared with MC, the diet of DF and HF mice increased by 4.42%, 10.38%, 5.87% and 7.08% respectively (p<0.05). The gastric residue reduced by 45.15% and 36.90%, and the small intestinal advance rate increased by 39.28% and 45.11% (p<0.05), respectively. Serum MTL and GAS levels increased by 35.94%, 39.05%, 32.14% and 38.45%, respectively (p<0.05). Studies have shown that R. roxburghii Tratt oral liquid has a good effect of promoting digestion and effectively promoting gastrointestinal motility.
