Effects of Coarse Cereal Vinegar Residue on Cholesterol Metabolism of Golden Hamsters
Article
Figures
Metrics
Preview PDF
Reference
Related
Cited by
Materials
Abstract:
To investigate the effects of coarse cereal vinegar residue on lipid metabolism in hamsters fed with a high-cholesterol diet, 30 hamsters were divided into three groups of 10, each with similar lipid levels and mean body weight: a high-fat group, a coarse cereal vinegar residue group, and a coarse cereal vinegar residue extract group. The concentrations of plasma total cholesterol (TC), LDL-cholesterol (LDL-C), HDL-cholesterol (HDL-C), and triglycerides (TG) were measured at 0, 10, 20, and 30 d. The contents of TC, cholesterol ester (CE), free cholesterol (FC), and TG in liver, and the contents of TC, total bile acid (TBA), lipids, and short chain fatty acids (SCFA) in feces were measured at the end of the experiment. Compared with the high cholesterol control group, coarse cereal vinegar residue and extract of coarse cereal vinegar residue significantly reduced serum TC by 22% and 15%, serum LDL-C by 35% and 21%, and liver TC by 15% and 14%, respectively, and increased the fecal TBA excretion by 23% and 16% and total fecal SCFA excretion by 30% and 9%, respectively (p<0.05). Coarse cereal vinegar residue may reduce TC and LDL-C levels in serum and TC and TG levels in liver by promoting increased excretion of fecal bile acids and SCFAs.
