Effect of Kaempferol and Quercetin on Blood Sugar and Fat Contents of Diabetic Model Mice
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Abstract:
The Anti-hypoglycemic effect of kaempferol and quercetin on diabetic model mice were studied. Two groups of diabetic model mice induced by alloxan were fed respectively with 2 doses of kaempferol and quercetin for 18 d. A group of non-model mice and a group of model mice fed with the same volume water were taken as the controls, and a group of model mice fed with Xiao ke wan (a Chinese medicine for diabete) was taken as the positive control. Then levels of serum glucose, TG, TC, MDA, and SOD and GSH-Px activities were investigated. The results showed that by kaempferol and quercetin, levels of serum glucose, TG, TC and MDA were significantly reduced, and SOD and GSH-Px activities were apparently enhanced. Among 2 doses of kaempferol and quercetin, 10 mg/kg bw?d was the modest one.